Scientists at Princess Margaret Cancer Centre have discovered that blocking the master regulator of bone renewal stops osteosarcoma - the most common primary bone cancer in children and teens, and the malignant disease that was fatal for Canadian icon Terry Fox.
Children With Cancer May Have Genetic Predisposition Even Without a Family History of Disease
Comprehensive genomic screening may be warranted for all pediatric patients with cancer, not just those with a family history of cancer. The finding comes from a detailed analysis of the role germline mutations in genes associated with cancer predisposition play in the development of childhood cancer.
Personalized Strategies Critical for Childhood Cancer
Genomic tools are helping to guide the search for new insights into uncommon childhood cancers like pediatric Acute Myeloid Leukemia (AML) and lymphomas — insights that, researchers hope, will improve survival rates and better spare survivors of childhood cancers from long-term treatment-associated health effects in adulthood, according to experts who spoke Saturday, December 5 at the 57th American Society of Hematology (ASH) Annual Meeting.